Postdoctoral Position Available
Tufts University School of Medicine-NEMC
Boston, MA
We have an immediate opening for a Postdoctoral Fellow to work in the
field of molecular signaling
and peptide-protein recognition. The project focuses on the yeast mating
peptide-receptor and the human thrombin
receptor. These receptors activate signal transduction pathways
culminating in cell cycle mitotic arrest in
the case of the yeast system and platelet aggregation in the case of the
thrombin receptor. Molecular
biology techniques will be used to construct recombinant receptors
and express these receptors in yeast
strains. Receptors will be characterized by various genetic and
physical methods, purified, and labeled with
affinity-peptides. Insight into the molecular interactions between these
peptides and their cognate receptors should provide leads for the
development of anti-thrombotic agents. The
laboratory is located within the Center of Hemostasis and Thrombosis
Research, a modern, state-of-the-art facility
with a staff of 20 investigators including technical support. Funds for
this position derive from an NIH Training
Grant in Hematology from the National Heart Lung and Blood Institute.
Qualifications for this position are a
Ph.D. degree and US citizenship or permanent residency. Candidates with
training in yeast genetics who would like
to acquire expertise in protein chemistry are encouraged to apply.
Interested candidates should send a
letter describing their research interests, a CV, and names of
three references to:
Athan Kuliopulos, MD., Ph.D.
Departments of Medicine and Biochemistry
Tufts-NEMC Box 832
750 Washington Street
Boston, MA 02111
617-636-5650
617-636-4833 (fax)
akuliopu at opal.tufts.edu
