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High school Labs

Helen McBride hmcbride at hlthsci.med.utah.edu
Wed Aug 2 13:09:38 EST 1995

Hi , 

     There is plenty that can be done with yeast to teach basic genetic
principles in even a JH school classroom. There is an entire program set
up out of KSU  called GENE (Genetics Education Networking and Enhancement
Project) funded by the NSF. They have manuals and videos covering
everything involved with using yeast as a classroom organism. They also
send out strains and have a deal with Bio101 to market pre-packaged media
for culturing. Some sample experiments are :

1) Using a triple DNA repair mutant to show how sunlight can cause
genetic damage (the mutant cells die, while healthy cells live when
exposed to 15 min of sunlight). 

2)Plasmid loss experiments using centromeric versus high copy plasmids
can show the function of centromeres and their role in mitosis. 

3) Isolating and characterizing spontaneous mutations in the adenine
biosynthesis pathway. This experiment can also be done with a germicidal
lamp  to contrast mutation rates (spontaneous vs. induced)

And there are many more things you can do with yeast!  If you would like
more info on how to get the manuals and videos e-mail me directly :

hmcbride at hlthsci. med.utah.edu

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