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5' ends and translational starts

Hoffmacs Hoffmacs at HERMES.BC.EDU
Thu Nov 17 07:12:09 EST 1994


Fellow smaller (not lower) eukaryote enthusiasts,
We did a primer extension that suggested transcription of a gene initiated
one nucleotide upstream from an ATG in the sequence.   Would such a
transcript be likely successfully to have a ribosome initiate translation on
the second through fourth nucleotides?  Is anyone aware of such a short 5'
untranslated region in any other gene (yeast or otherwise).  Thanks for any
input.
Charlie Hoffman
"I'd rather be fission."



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