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Extra sequence at ends of telomeres - help

Anthony Tomlinson anthony at pplros.demon.co.uk
Fri Aug 26 08:31:16 EST 1994


Sorry if this is a FAQ or patently obvious, but-

Does anyone know if having about 12 bp of spurious DNA (NotI plus half a
BamHI site) on the TEL end of a linearised YAC arm affects its stability?
 Does the extra sequence mask the telomere, and/or is it chewed back
until the telomere is exposed?
Thanks

Anthony



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