Tae Hoon Kim wrote:
>Hello. I am an undergraduate student working on a senior thesis project
>involving the possible relationship between senescence and programmed cell
>death. A small part of my thesis deals with evolution of cell death
>mechanisms in relation to programmed cell death and cellular senescence.
>I have ran across some interesting literature on yeast senescence.
>>Scar on the cell wall of S cerevisiae limits the potential number
>of cell budding before the mother cell autolysis. Based on the surface area
>the maximum potential number of buddings before the entire cell wall is
>covered with budding scars is about 100. Is it true that observed number
>of budding before autolysis is smaller than the limit set by the cell wall
>area?
>>I would appreciate any comments concerning this matter.
>>Regards,
>Tae Hoon Kim
>tkim at reed.edu>Reed College
>>Take a look at:
Jazwinski SM. Chen JB. Sun J. |
A single gene change can extend yeast life span: the role of Ras in |
cellular senescence. [Review] |
Adv Exp Med Biol. 330:45-53, 1993. |
Also look at earlier papers by Jazwinski.
Preston Garrison
Biochem. Dept.
UTHSCSA
San Antonio, Tx 78284-7760
USA
garrisonp at uthscsa.edu