Hello. I am an undergraduate student working on a senior thesis project
involving the possible relationship between senescence and programmed cell
death. A small part of my thesis deals with evolution of cell death
mechanisms in relation to programmed cell death and cellular senescence.
I have ran across some interesting literature on yeast senescence.
Scar on the cell wall of S cerevisiae limits the potential number
of cell budding before the mother cell autolysis. Based on the surface area
the maximum potential number of buddings before the entire cell wall is
covered with budding scars is about 100. Is it true that observed number
of budding before autolysis is smaller than the limit set by the cell wall
area?
I would appreciate any comments concerning this matter.
Regards,
Tae Hoon Kim
tkim at reed.edu
Reed College