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Morris F. Manolson mm6y+ at andrew.cmu.edu
Sat Apr 17 13:29:27 EST 1993

>OK. I am a biochemist who works with a large, furry multicellular 'yeast'
>-otherwise known as a mouse. If I want to work on a real yeast, it is a 
>major shift in thinking/methods/strategies. Question: what is the best 
>book that might let me start to explore the yeast system - specifically for
>protein degradation studies,  but that may not be relevant - from the
>idiot's guide to the sophisticated manuals. Do they exist?
>(I also appreciate that there is no substitute for talking to or working
>with a real expert!)

The book which has remained opened on my desk since I bought it and is
falling apart after only six months (I got the cheep binding)
and that is packed full of excellent methods and theory and is 
the best yeast methods book to date is:

Guide to Yeast Genetics and Molecular Biology
Ed. by Guthrie and Fink
Methods in Enzymology, Vol 194.

For methods there is also a decent chapter in that hugh red methods book
called "Current protocols in molecular biology"  Check out
chapter 13 which is on Saccharomyces cerevisiae.

For less methods and more theory I would highly recommend the 
series of Books called "The molecular Biology of the yeast Saccharomyces"
published by Cold Spring Harbor.  There is two volumes published
around 1981 and two new volumes which have just been released.

Hey Francis, do I have to add those disclaimers at the bottem saying that
I don't work for any of these publishing houses etc etc?  All right,
I'll come clean.....my ex-boss is one of the editors of the cold spring
harbor volumes...but thats it!  No other affiliations.  ;->  Morrie

Morris F. Manolson                     Tel:  416-813-6662  (office)
Division of Cell Biology                     416-813-5729  (lab)
Hospital for Sick Children                   416-813-5028  (FAX)
88 Elm St., McMaster building        email:  Morrie at resunix.ri.sickkids.on.ca
Toronto, Ontario, Canada
M5G 1X8

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