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Dr.R.S.Rao rsrao at BLR.VSNL.NET.IN
Mon Feb 1 01:48:19 EST 1999



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> From: Dr.R.S.Rao <rsrao at blr.vsnl.net.in>
> To: toxicology <toxicol at net.bio.net.>
> Subject: wish to subscribe, to receive e-mail of discussion group. 
> Date: 23 January 1999 16:39
> 
> Hello, 
> 
> I wish to subscribe, to receive e-mail of discussion group. 
> 
> I have a query regarding, formulating compounds, to carry out acute and
> subacute toxicity studies,through parenteral 
> route,particularly,I.V route,in rodents. 
> 
> I wish to know what are the common vehicles and solvent used,for
parenteral
> route of administration(I.V and I.P)? What is the 
> concentration and total amount of these can be administered,without
causing
> side effects? In order to achieve the high 
> concentration required,especially to carryout acute studies,(particularly
> the compounds which are not water soluable)what 
> procedures to be adapted? 
> 
> I shall be thankful.if any one could help me in these aspects. 
> 
> Regards--------------R.S.Rao. 
> 



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