Two hypotheses seems to emerge to explain metal carcinogenicity:
induction of oxidative damage and interaction with DNA repair. However,
can metals cause promutagenic damage such as DNA strand breaks !!! I
am looking for any relevant reference underlying the mechanism.
Thanks for any help or reference.
E-mail: assad at justine.umontreal.ca
* Michel Assad
* Paediatric Research Center
* Ste-Justine Hospital
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