ahstern at EOHSI.RUTGERS.EDU (Alan Stern) wrote:
>Jim Laughlin wrote that he did not think that there were any animal
>models for cadmium toxicity.
>>I may be missing the context of this discussion, but Friberg's CRC book (I
>beleive that the title is "Cadmium in the Environment" presents detailed
>discussions of rodent models for cadmium nephrotoxicity, which look to be a
>pretty good model for the similar adverse effect in humans.
>>>Alan Stern, Dr.P.H., D.A.B.T.
Why would rodent models for dadmium nephrotoxicity be a "good model" for
the similar adverse effects in humans? If we can sort out why
toxicologists feel that the rodents are good models for cadmium toxicity
in humans, then I think we may have something substantial to contribute
to the discussion on animal models.
John A. Budny