The following two messages were forwarded for Professor M.C.AGRAWAL
>Writing of Monograph on Asian/Indian schistosomes and schistosomiasis.
>A lot of work has been done on Indian schistosomes and schistosomiasis but most of the work has been
>published in Indian journals with little assess by international scientific community. Nevertheless,
>knowledge of the work is very important specially to those international scientists who are working on
>phylogeny, biology of schistosomes, drug response, heterologous mating,comparative pathology etc. Since
>most of the work is scattered, the scientific community is not able to analyse the work carried out in India
>and adjoining countries.
>The undersigned has worked extensively on different aspects (immunity, diagnosis, zoonotic potentials,
>epidemiology, blood biochemistry, host susceptibilities , techniques etc ) of Indian schistosomes for last thirty years and has retired as Dean/Professor and Head, Department of Parasitology, College of Veterinary Science and AH,Jabalpur on 31st Jan, 2005. Therefore, he is interested to write a monograph on Indian schistosomes and schistosomiasis
>caused by them in different countries. Certainly, the job is extensive, requires collaborations, finances hence appeal any scientific organisation/institution/scientist who is interested to join the project.
>M.C.AGRAWAL,4th June, 05
Triclabendazole in schistosomiasis.
We are working on Indian schistosomes since last three decades. Among the work, we tried Praziquantel,
Oxamaniquine against Schistosoma incognitum/S.spindale in mouse/pigs but with insignificant results. As
triclabendazole is used against fascioliasis in bovines, we tried it first in S.incognitum-mouse model
and then in cattle harboring schistosomiasis. The drug is killing immature blood flukes to significant levels
and mature to the level of other drugs.
Therefore, in our opinion, there is a case to try triclabendazole in schistsomiasis; also where host is
harboring both fasciola and schistosomes. Our paper on Triclabendazole on hepatic bovine schistosomiasis is
appearing in June 2005 issue of Indian Journal of Animal Sciences, published by Indian Council of
Agriculture Sciences, New Delhi.
It will be our pleasure to collaborate with any one in this adventure.
M.C.AGRAWAL , 4th June, 2005