Rex Eastbourne wrote:
> Thank you, Austin! Very helpful.
>> I've got a better description of what I need to do now. I have a
> collection of proteins in a spreadsheet, and need to find out:
>> -Are some of them related to one another?
> -Do they participate in a single transduction pathway in the cell or
> between cells?
>> Does this sound like a hard task for someone with lots of math but no
> bio?
Hi Rex...
If it is a matter of "relationship" (in the sense that a set of proteins
behave i.e. go up or down in the same way over a given treatment), then
any k-means algorithm will do the trick. I'm pretty sure this would be a
no-brainer for you. I'm actually surprised they don't give it a go by
themselves...
Anything else (like your second point...though I'm curious about the
experimental design) you'd have to give more details, say:
col1=proteinID
col2=expt1
col3=expt2
etc...
BTW...If you don't want to do it, then don't. Technically, if the person
is doing a PhD, then he/she should know how to do it themselves anyway
and not just hand it off...
Austin
P.S. what is your math background? I should have probably asked that
first...
