Are you interested in RATIONAL DRUG DESIGN?
X-ray crystallographic visualization of an inhibitor which is a =
potential drug in the active site of an enzyme done by a group of South =
African researchers
The First African Structural Biology Conference
Macromolecular Structure, Health and Biotechnology in Developing =
Countries
The Wilderness, South Africa
24-27 October 2006
The First African Structural Biology (FASB) conference will be held in =
The Wilderness, South Africa. Structural Biology is fundamental to =
rational drug design and central to the drug discovery process. We are =
fortunate in having a number of speakers who have been successful in =
this area and who have applied their minds to the diseases of the =
developing world.
Expression of interest and registration forms can be submitted online by =
visiting our website:
http://sbio.uct.ac.za/conference
Programme
Tuesday 24 October 2006
2:00 pm
Dr P Mjwara (Department of Science and Technology, South Africa).
3:00 pm
Prof Sir Tom Blundell, FRS (University of Cambridge, UK).
Structural Biology and Modern Drug Discovery.
4:00 pm
Tea
4:20 pm
Prof Wieland Gevers (ASSAf, South Africa)
Introduction of ASSAf Speaker Joachim Frank
4:30 pm
ASSAf Lecture
Dr Joachim Frank (Howard Hughes Medical Institute, USA).
The Ribosome in Motion as seen by Cryo-EM.
5:30 pm
Prof Iain Campbell (University of Oxford, UK).
The role of NMR in structural biology and drug discovery.
6:30 pm
Dinner
7:30 pm
Poster Session
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Wednesday 25 October 2006
8:00 am
Dr Gert Vriend (University of Nijmegen, Holland).
Protein Modelling.
9:00 am
Dr Steve Bryant (NCBI, USA).
Protein Classification Methods for NCBI's Conserved Domain Database.
10:00 am
Contributed Papers
10:30 am
Tea
11:00 am
Prof Christian Sommerhoff (University of Munich, Germany).
Parasite-derived Inhibitors of Mast Cell Proteases: Templates for Drug =
Development.
12:00 pm
Prof Ravi Archarya (University of Bath, UK).
Structure based design of new ACE inhibitors through Cape Town (South =
Africa) - Bath (UK) link.
1:00 pm
Lunch
2:30 pm
Dr Rolf Boelens (University Utrecht, Netherlands)
3:30 pm
Bruker Lecture
Dr Rudiger Weisemann (Bruker, Germany)
NMR Spectroscopic Studies of Protein/Ligand interactions.
4:00 pm
Tea
4:20 pm
Contributed Papers
4:40 pm
Contributed Papers
5:00 pm
Contributed Papers
6:30 pm
Dinner
7:30 pm
Posters
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Thursday 26 October 2006
8:00 am
Prof James Sacchettini (Texas A&M University, USA).
Combining Structural Genomics and Drug Discovery to Develop New TB =
Drugs.
9:00 am
Dr Peter Kwong (National Institute of Health, USA).
10:00 am
Contributed Papers
10:30 am
Tea
11:00 am
Prof David Rice (University of Sheffield, UK).
>From drugs to herbicides: the impact of structural biology on rational =
design.
12:00 pm
Prof Krishna Murthy (Alabama University, USA).=20
1:00 pm
Lunch
2:30 pm
Canoeing on the Wilderness Lagoon sponsored by Rigaku MSC
6:30 pm
Gala Dinner
7:30 pm
Posters
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Friday 27 October 2006
8:00 am
Prof Karolin Luger (Colorado State University, USA).=20
Of nucleosomes, viral hitch-hikers, and chaperones.
9:00 am
Prof Andreas Hoenger (University of Colorado at Boulders, USA).
Structural Investigations into the Interaction between Microtubules and =
Mal3p, an S.pombe Homologue of EB1.
10:00 am
Contributed Papers
10:30 am
Tea
11:00 am
EMBO Lecture
Prof Helen Saibil, FRS (University of London, UK).=20
One Sequence, Two Structures: protein conformational changes that cause =
disease.
12:00 pm
Prof Edward Egelman (University of Virginia, USA).=20
Order, Disorder and Heterogeneity in Helical Polymers.=20
1:00 pm
Lunch
2:30 pm
Prof Igor Polikarpov (University of Sao Paulo, Brazil).
Structural Studies of HIV Proteases of Subtype B and F and their =
Mutants.
3:30 pm
Prof Mamannamana Vijayan (Indian Institute of Science, India).
Structural biology of Mycobacterial Proteins the Indian Scenario.
4:00 pm
Tea
4:20 pm
Dr Frank Von Delft (Structural Genomics Consortium, Oxford UK)
4:40 pm
Dr Bethuel Sehlapelo (Department of Science and Technology, South =
Africa).
5:00 pm
Discussion
6:30 pm
Dinner
7:30 pm
Posters
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Conference Organizer:=20
Trevor Sewell
Institute of Infectious Disease and Molecular Medicine
Wolfson Pavilion, Level 3
Faculty of Health Sciences
University of Cape Town
Anzio Road
Observatory,
7925
South Africa Tel.: +27-21-6502817
Fax: +27-21-6891528
E-mail: sewell at uctvms.uct.ac.za
Conference Organizing Committee:
Dr Arvind Varsani (arwind at science.uct.ac.za)
Professor Girish Kotwal (gkotwal at curie.uct.ac.za)
Professor Ed Sturrock (sturrock at curie.uct.ac.za)
Dr Muhammed Sayed (msayed at uwc.ac.za)
Dr David Pugh (dpugh at uwc.ac.za)
Miss Eulashini Chuntharpursat (eulashini at uctbc1.uct.ac.za)
Mrs Miranda Waldron (mwaldron at uctvms.uct.ac.za)
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