The Center for Structural Molecular Biology (CSMB) at Oak Ridge National
Laboratory seeks a research associate/technician. The group is engaged
in research related to protein structure and function using small angle
scattering and crystallographic techniques. As a member of CSMB, the
candidate will be responsible for purifying and characterizing a wide
variety of recombinant proteins. This requires conducting scientific
research in protein biochemistry and recombinant DNA technology. The
successful candidate will be responsible for critically analyzing and
interpreting data, and preparing technical reports and project
summaries.
This position will be responsible for purifying recombinant proteins
from bacterial or eukaryotic sources using a variety of techniques
including column chromatography, centrifugation, ultrafiltration,
refolding, and differential precipitation. In addition, familiarity with
recombinant DNA techniques including PCR, DNA cloning techniques, and
mutagenesis is necessary. Prior experience in fermentation and protein
expression is desirable but not essential. The successful candidate will
assist in the maintenance and general running of the laboratory and
provide technical support to other group members. The position requires
excellent organizational skills with the ability to work independently
and to handle several ongoing projects at once along with keeping
accurate and complete research records.
M.S. in biology, biochemistry, molecular biology or a related
discipline, or the equivalent knowledge and experience, is required.
Applications with curriculum vitae and the names of three referees
should be sent to:
Dr. Hugh O'Neill,
Chemical Sciences Division,
Oak Ridge National Laboratory,
P.O. Box 2008 Oak Ridge,
TN 37831-6194
oneillhm At ornl.gov
