D.K. wrote:
> >Ionic and hydrogen bonds involve hydrophilic groups.
>> I am not an expert but perhaps for precisely this reason I
> cannot offhand think of a case where specific high affinity
> interaction occurs between highly acidic and highly basic faces of
> two proteins. I am sure there are few cases like that but it's
> probably more of an exception...
This probably depends very much on the individual proteins. As example
for ionic interactions in proteins haemoglobin subunits (and Bohr
effect) would spring to mind...