folding structure of this glycoprotein

w2hgcg at netscape.net w2hgcg at netscape.net
Sat Jun 12 07:05:39 EST 2004

I have not subscribe to this malling list, I have not found how to... so please mail me back directly and not just to the mailling list, thanks in advance. 
I have four seuences (amino acid) of closely related genotypes in a viral complex. I need to predict the folding structure of this glycoprotein gene which is about  1640 amino acids long. I need to draw the 3D structure using the disulphide bonding with cyctine residues. I have the cleavage sites which have generated the two mature proteins. It is translated as a polyprotein and cleaved to genetate 2 mature proteins which are predicted to be glycosylated.
 what I really want to know whether the changes in the AA sequence will alter the 3D structure os these strains compared to the base sequence structure. I have the sequence of the two prototype strains. any hints are more than wellcome... cheers

Introducing the New Netscape Internet Service. 
Only $9.95 a month -- Sign up today at http://isp.netscape.com/register

Netscape. Just the Net You Need. 

New! Netscape Toolbar for Internet Explorer
Search from anywhere on the Web and block those annoying pop-ups.
Download now at http://channels.netscape.com/ns/search/install.jsp

More information about the Proteins mailing list

Send comments to us at biosci-help [At] net.bio.net