steps and problems for 3-D structure determination

[Marc Parisien]

Hi All!

    Where could I look for the steps involved in 3-D structure
determination (either X-Ray or NMR), and also where in these steps are
problems that could be resolved by computer and/or better algorithms. I
would guess that the steps/problems are the same for either RNA or
proteins?

    thanks for your time,
    Marc.