Biochesitry is changing. Through advances in methodology, experiments
can now be done with orders of magnitude less sample volume. It is now
possible to do PCR on the nanoliter scale. For hard to make samples
this economy of scale opens up whole new areas of study. The
chromatography still needs to be reproducible and precise which is why
finding the right components is preferable to aftermarket modifications
to pipet tips.
I don't know how long anyone has been doing biochemistry, and I've made
my share of things out of legos and tape. I was looking for assitance
in finding materials. I appear to have tapped into some deep rooted
resentment towards people you feel are trying to cut corners.