Hi,
What could it mean if two highly related proteins, clearly the product of a
duplicated gene, differ mainly in their proline content. One of the proteins
has a normal low protein content (about 3 %) but among a limited number of
differences in many cases the difference is that the second protein has a
proline where the first does not, bringing the percentage on more than 12 %.
These mutations occur throughout the protein but the DNA-binding (homeo-)
domain has been spared, wheress a second 'conserved' is not.
--
Frits
