IUBio

Protein denaturation.

Lars Carlsson 018-422429 at telia.com
Fri Mar 16 03:37:29 EST 2001


Frank wrote:
"Frank Fuerst" <ffrank at rz.uni-potsdam.de> wrote in message news:9805ai$qus0f$5 at fu-berlin.de...
> "andrzej f. lyskowski" <jendrekl at poczta.onet.pl> wrote:
> 
> Denaturation: 
> - Heat works always,
> - cold works sometimes
> - urea or guanidinium chloride are common chemical denaturants.
> 
> How they work? Nobody really knows, at least for the chemicals. They
> do.
> 
> Bye, Frank



Urea and guanidinium chloride works by replacing the hydrogen bonds from water and the polypeptide chain itself!

Lars C.


-- 
Lars Carlsson
lars-carlsson at telia.com


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