Psi amino acids?

ChenHA hachen at bc.ic.ac.uk
Fri Feb 18 11:33:59 EST 2000

On 16 Feb 2000, Mina wrote:

> Recently, I found a consensus sequence described as : psi - K - X - E.
> Can somebody tell me which amino acids belong to "psi", what
> classification is that or just point me to a reference.

one possibility is that psi stands for pseudo - i.e. it means that the
amino acids may be a pseudo-amino acid such as pseudo-proline or
whatever residue that is unnatural or unusual.   For example, the CO
or NH group may be replaced by CH2 group so that the peptide bond
becomes non-hydrolysable, or the side-chains has other atoms or groups
attached or replaced.

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