PMSF dire straits

BHKim byung-hoon.kim at uni-tuebingen.de
Tue Feb 1 06:21:34 EST 2000

"Frank O. Fackelmayer" schrieb:

> HOWEVER, stability of PMSF is hardly ever a concern because its mode of action.
> It covalently modifies the active center of many (serine) proteases, and makes
> them proteolytically inactive. This modification is fast, and once it happened it
> is irreversible, so you really donut have to care about breakdown of the excess
> PMSF afterwards.

> Frank

I'm not sure, but I've heared that it can be reversible when there is reducing power
(like DTT) in the solution.


More information about the Proteins mailing list

Send comments to us at biosci-help [At] net.bio.net