Just started on the subject of enzyme inhibitors and already have been
asked to draw a mechanism for cleavage of fructose 1,6 bisphosphate as
catalyzed with the help of a lysine side chain in the enzyme aldolase.
I don't know where to begin since our textbook did not have examples of
mechanisms of enzyme inhibitors.
Others:
1) Draw the structures of the expected products of the yeast alcohol
dehydrogenase (YADH) reaction with undeuterated acetaldehyde and NADH
in D2O solution.
2) Mechanism for the inactivation reaction of tosyl-L-phenylalanine
chloromethyl ketone (TPCK) with chymotrypsin. TCPK inhibits
chymotrypsin by covalently labeling His57 >>> indicate structure of the
product(s). Based on the structure of TCPK what reagent might be an
effective inhibitor of trypsin?
Can anyone help me out? Thanks.
--
Posted via Talkway - http://www.talkway.com
Exchange ideas on practically anything (tm).
