IUBio

PI change

M.Takeda takeda at ims.u-tokyo.ac.jp
Wed Nov 24 08:35:50 EST 1999


Hi

  How much PI(Isoelectric point) value is changed when one phosphate is
covalently incorporated into protein.

  Does anyone knows about the relationships between PI change and
post-translational modification of protein(this modification changes PI
0.05pH, and so on)?    Is there a any text book or reference regarding
this?(or computer program which can automatically culculate PI from primary
sequence with a optional command to point out this residue is
phosphorylated).

--------------------------
M.Takeda

IMS, U. of Tokyo, Japan

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