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Can proteinase inhibitors penetrate the cell membrane?

Dima Klenchin klenchin at facstaff.REMOVE_TO_REPLY.wisc.edu
Tue Nov 16 12:35:51 EST 1999


:
:Hi, all
:
:Can proteinase inhibitors (Aprotinin, Leupeptin and Pepstatin) penetrate
:the cell membrane?

Aprotinin and Leupeptin cannot for sure. Pepstatin, being a hydrophobic
peptide, probably can, but probably not very efficiently. 

        - Dima




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