even at pH 14?
I though any OH group is analog of water. then should be ionizable
In article <Pine.GSO.4.05.9906031209120.14933-100000 at cbl.umces.edu>,
reno at cbl.umces.edu says...
>>>Hi,
>>Check out the URL address
http://www.proteometrics.com/aainfo/contents.htm
>You'll find info on the pKa values for the side chains of amino acids
that
>ionize. Threonine's hydroxy side chain does not ionize. You won't find
>any pKa value for Thr, other than for its alpha amino and carboxyl
groups.
>Only the side chains of the following amino acids will ionize:
>>Arg (guanido group)
>Asp (beta carboxylic acid)
>Cys (sulfhydryl)
>Glu (gamma carboxylic acid)
>His (imidazole)
>Lys (epsilon amino group)
>Tyr (phenol)
>>>Reno Nguyen
>>>On Thu, 3 Jun 1999, Steffen Schmidt wrote:
>>> Date: Thu, 03 Jun 1999 07:49:30 +0200
>> From: Steffen Schmidt <sschmid2 at Uni-MolGen.gwdg.de>
>> Newsgroups: bionet.molbio.proteins
>> Subject: pk of Threonin
>>>> Hi,
>>>> does anyone know the pk-value of the hydroxy-group of threonin, or a
>> citation where I can find it.
>>>> Thanks, Steffen
>>>>>***********************************************************************
**
>Reno T. Nguyen
>Chesapeake Biological Laboratory /----\ /-----\ /
>Univ. MD Center for Environmental Science / / / /
>P.O. Box 38 / /______/ /
>Solomons, MD 20688 / / \ /
> / / //
>Tel: (410) 326-7261 \_______/ \_______/
\_______/
> (410) 326-7409
>Fax: (410) 326-7341
>E-mail: reno at cbl.umces.edu>***********************************************************************
*
>>
