In article <Pine.GSO.4.05.9908131111210.6257-
100000 at cbl.umces.edu>, "Reno T. Nguyen" <reno at cbl.umces.edu>
wrote:
>On Fri, 13 Aug 1999, KuS wrote:
>>> Hello,
>>>> I would just like to know if the principles of the freeze-drying in a
>> lyophilizator and in a speed-vac machine are the same?
>>>> Thanks,
>>>> Barbara (info at kos-computers.si)
>>>Hi Barbara,
>>Well, although both freeze-drying (lyophilization) and speed-vac drying
>involve pulling a vacuum on your samples, the process of removal of water
>in each instrument is different. With freeze-drying, the samples are
>frozen, and water is removed through the process of sublimation- solid
>water is lost as a gas. With a speed-vac, the sample is not frozen but is
>usually heated in a chamber while being spun at high rpm's; liquid water
>is lost as a gas.
>>Reno
>
Nothing prevents you from using the speed-vac as a
lyophilizer, however, by freezing your samples first (as I
do).
Nick
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