Hi, I got a private reply from somebody whose newsserver didn't work:
From: "L. Guan" <lguan at is.icc.u-tokai.ac.jp>
To: Frank Fürst <ffrank at rz.uni-potsdam.de>
Subject: Re: Inclusion bodies
Date sent: Tue, 3 Aug 1999 19:12:02 +0900
Would you please let me know if inclusion body is lethal to cells? I
my mutants go to die if I use high concentration induction.
And, whether still have some native comformation protein out of
body when inclusion body
forms? I restored the function of one of my mutants at 28 C. and also
partial function with low level induction. It seems the mutation do
attack the folding important structure.
Since I can not post this, sorry to bother you.
Thanks in advance!
Department of Molecular life Science
Tokai University School of MedicineJapan