Applications for postdoctoral and research assistant positions are=
immediately available in my laboratory. Candidates should be highly=
motivated and have good expertise in molecular biology, biochemistry and/or=
cell biology techniques. Candidates with experience in yeast two-hybrid=
system and/or general protein chemistry are particularly attractive.
Current work underway in the laboratory focus on studying biogenic=
steps of G- protein coupled receptors and phosphoinositide signaling in=
neuronal cells. We have been particularly interested in investigating i)=
the molecular mechanisms underlying the function of a new neuronal=
signaling pathway mediated by a novel PI-phospholipase C (e.g. Ferreira, P.=
et al. (1994). J. Biol. Chem., 269, 3129; Ferreira, P. et al. (1993) Proc.=
Natl. Acad. Sci. USA, 90, 6042) and, ii) the molecular machinery involved=
in the intracellular processing and trafficking of homologous G-protein=
coupled receptors in highly polarized neuronal cells (e.g. Ferreira et al.=
(1998), J. Biol. Chem. submitted; Ferreira, P. et al. (1997) Proc. Natl.=
Acad. Sci. USA, 94, 1556; Ferreira, P. et al. (1996) Nature 383, 637;=
Ferreira, P. et al. (1995) J. Biol. Chem. 270, 23179). In addition, we are=
using our studies as a model system to study widespread homologous=
molecular mechanisms in other biological systems and understand the=
molecular pathogenesis underlying certain inherited neurological disorders=
in humans which ultimately lead to the degeneration of selective neurons in=
the CNS. The laboratory and institution are equipped with state-of-art=
facilities and operate in an outstanding research environment. The=
prospective candidate is expected to participate in campus-wide interactive=
programs such as seminars and ultimately, present his\her research results=
at international meetings and publish in top-rated scientific journals. =
Salary is based on experience and NIH guidelines.
Candidates with an overall interest in neurobiology are invited to=
apply and should send their CV, summary of their past research experience=
and future goals, and three reference letters directly to:
Paulo A. Ferreira, Ph.D.
Medical College of Wisconsin
Pharmacology Department
8701 Watertown Plank Road
Milwaukke, WI 53226
Phone: 414-456-8877
Fax: 414-456-6545; =20
Email: ferreira at post.its.mcw.edu
<bold><color><param>0000,0000,8080</param>Paulo A. Ferreira, Ph.D.
Assistant Professor
</color></bold><color><param>8080,0000,0000</param>Medical College of
Wisconsin
Pharmacology Department
8701 Watertown Plank Road
Milwaukee, WI 53226
FAX: 414-456-6370 // -6545=20
Phone: 414-456-8877 // -8267; Lab: -8043</color>