IUBio

Question about signal sequences.

Mary P. Remington mremingt at umaryland.edu
Sun May 17 06:33:58 EST 1998


     We are expressing a fusion protein and then overlaying it onto cells.
This protein is taken up by the cells but we would like it to be moved
inside the cell to the membrane.  What signal sequences would target this
protein from the cytoplasm to the cell?  I have thought of maybe using
part of a retrovirus env sequence to target the protein.  Any other ideas?
Thanks, Mary




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