IUBio

phosphoryalation patterns MAPK

Phillip Robinson phrobins at mail.usyd.edu.au
Fri Sep 12 01:03:29 EST 1997


> Does anybody know where I can find information on the consensus
> sequences used as phosphorylation sites for kinases in general,
> especially MAP kinases? Does there exist software to screen
> for consensus phosphorylation patterns in protein sequences?

Try Methods in Enzymology vol 200/201, especially chapters by Rick
Pearson/Bruce Kemp for excellent summaries.  Another good source is "The
protein kinase Facts Book" by G Hardie/S Hanks and Academic Press.
A computer search of Prosite will reveal many phosphorylation sites. 
However, just remember that these are *predictions* only and are
sometimes a mile off reality.  I don't know of any other programs.

Phil
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Children's Medical Research Institute      ,
      Sydney, NSW AUSTRALIA            ;--_|\
                                      /      \
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    phrobins at mail.usyd.edu.au         \_;--._/
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