In article <331DAAB6.11BF at mail.utexas.edu>, brettsp at mail.utexas.edu wrote:
> Does anyone have a good reference on determining a proteins radius of
> gyration. I do not know much about this and I do not know what has to be
> known about the protein before this can be done, ie do you have to know
> the crystal structure of the protein first?
>Try Physical Chemistry of Macromolecules, by Charles Tanford.
If I remember correctly, and it's been a while, it's a statistically
defined parameter that describes the sphere swept out by the "mass
elements" of the peptide chain (or other atoms of whatever molecule). IF I
remember correctly it's the radius measured in light scattering
experiments, though there are other ways.
--
Jim Litts
Zymogenetic, Inc.
Seattle, WA USA
My comments are my own and not my employer's.
