Hello!
Well, the Bovine Papillomavirus DNA binding domain (minimal) iosonlt 85 AA
although tit forms a dimer. It has the aadvantage of many characterized
mutations, and an excellent crystal structure (1.2A) and binds
sequence-specific to a palindropme at 10 -12 M.
I also study it!
John
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John Strasswimmer, MD,PhD Candidate | Phone (617) 636 8396
Tufts - New England Medical Center | Fax (617) 636 6190
Box 166 | Email: jstrassw at opal.tufts.edu
Boston, MA 02111 USA |
HTTP://WWW.healthsci.tufts.edu/microbiology/strass/JSpage.HTML
*** Co-Author of "HyperBug" Microbiology Teaching Software ***
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On Fri, 10 Jan 1997, MThompson wrote:
> I am searching for a small independently folding (or in presence of a
> metal ion), DNA binding domain. Would like it to be sequence specific, but
> would greatly appreciate all suggestions. Be as detailed as possible or
> please cite a reference, or name that I can locate it in the literature.
> Thanks very much.
>>
