Dear Toukie,
I believe the toxin ricin acts this way and can be coupled to
antibodies to target specific cell types. It is extremely toxic,
killing cells at very low molecules/cell ratios.
Dennis Goode
> To:
proteins at net.bio.net
> From: toukie at zui.unizh.ch (Hr Dr. S. Shapiro)
> Subject: Seeking receptor information
> Date sent: Wed, 24 May 1995 07:16:06 GMT
> Dear Colleagues;
>> Does anyone know of a small molecular-weight molecule which, when bound
> to a (specific) receptor on a cell surface, is capable of eliciting leakage
> of cytoplasmic contents and eventually inhibition of cell growth or cell death?
> If so, kindly send details, inlcuding relevant references, to me at
>>toukie at zui.unizh.ch>> Thaks in advance to all responders.
>>> Sincerely,
>> S. Shapiro
> ZH
>toukie at zui.unizh.ch>>
