I will not discuss the details of the work I heard about,
because it is not published and not my own work.
I *did* overstate its success, though.
It is *not* a solution to the folding problem.
It is clever,though, does work (somewhat, sometimes), and
suggests that in ten years, the folding problem will
perhaps be solved.
This is all I have to say. I'm very sorry to have
brought it up. Everyone (including me, for some details)
will have to wait for the paper to appear, which should
be within a few months.
I will never post about unpublished work, interesting
or not, again.
Now please, let up.
--JK
In article <3o9fau$9a3 at news.iastate.edu>, baker at iastate.edu (Wayne R. Baker) writes:
|> In bionet.molbio.proteins, David Jones <jones at bsm.bioc.ucl.ac.uk> wrote
|> :
|> :Unfortunately there seem to be three diverse groups of people here.
|> :The first group seem to have been to one of George Rose's seminars.
|> :The second group have heard some rumours and have not been to one of
|> :George Rose's seminars - but would like to.
|> :The third group (which certainly includes me) have heard absolutely
|> :nothing about this supposed breakthrough - until now. Perhaps I'm the
|> :only one in the third group? Hands up all those who have heard about
|> :this work by George Rose... oh dear, how embarassing - just me, then!
|>|> You're not the only one, although I'm a wee bit behind in my journals. :-(
|>|> :Just to make some use of the wasted bandwidth here - why doesn't
|> :someone in the first group let us in the third group in on what's
|> :supposed to be going on. If he's spoken about this at a seminar then
|> :a brief synopsis isn't going to hurt anyone - then we can _all_
|> :enjoy the suspense until the paper comes out!
|>|> I second the motion. All in favor...?<loud roar> Opposed...?<chirp
|> chirp> The ayes have it!
|>|> Rose did publish something on helix forming propensities in "Proteins"
|> last year, but the work is now nearly two years old. Last March, Scheraga
|> seemed to think he was close to a solution. Levitt also seemed like he
|> was on to something as well. At the Beckman conference last June,
|> Patrick Argos showed some results for simple systems that were pretty
|> impressive. I'd be interested in how Rose's algorithm compares.
|>|> Anyone care to scoop Dr. Rose? :-)
|>|> Wayne Baker (baker at iastate.edu) Maybe a great magnet pulls
|> Biochemistry & Biophysics All souls towards truth
|> Iowa State University -- k. d. lang, "Constant Craving"
--
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John Kuszewski || |/ /| ||
johnk at spasm.niddk.nih.gov || / /|| ||
\/ / / || \/
that's MISTER protein G to you! |/__/| |
/_________|
"Biophysics has driven me to an attitude of apocalyptic doom"
--Frank Delaglio
