IUBio

A Plea To John K! (was Re: Comment to S.Blocklehurst)

Wayne R. Baker baker at iastate.edu
Wed May 3 21:49:02 EST 1995


In bionet.molbio.proteins,  David Jones <jones at bsm.bioc.ucl.ac.uk> wrote
:
:Unfortunately there seem to be three diverse groups of people here.
:The first group seem to have been to one of George Rose's seminars.
:The second group have heard some rumours and have not been to one of
:George Rose's seminars - but would like to.
:The third group (which certainly includes me) have heard absolutely
:nothing about this supposed breakthrough - until now. Perhaps I'm the
:only one in the third group? Hands up all those who have heard about
:this work by George Rose... oh dear, how embarassing - just me, then!

You're not the only one, although I'm a wee bit behind in my journals. :-(

:Just to make some use of the wasted bandwidth here - why doesn't
:someone in the first group let us in the third group in on what's
:supposed to be going on. If he's spoken about this at a seminar then
:a brief synopsis isn't going to hurt anyone - then we can _all_
:enjoy the suspense until the paper comes out!

I second the motion. All in favor...?<loud roar> Opposed...?<chirp
chirp> The ayes have it! 

Rose did publish something on helix forming propensities in "Proteins"
last year, but the work is now nearly two years old. Last March, Scheraga
seemed to think he was close to a solution. Levitt also seemed like he
was on to something as well. At the Beckman conference last June,
Patrick Argos showed some results for simple systems that were pretty
impressive. I'd be interested in how Rose's algorithm compares. 

Anyone care to scoop Dr. Rose? :-)

Wayne Baker (baker at iastate.edu)		Maybe a great magnet pulls
Biochemistry & Biophysics		All souls towards truth
Iowa State University			-- k. d. lang, "Constant Craving"



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