Classification of Acyl Carrier Protein

POSTMAST at gunbrf.bitnet POSTMAST at gunbrf.bitnet
Fri Nov 2 19:30:00 EST 1990

Beverly Seavey writes:
> does E. coli acyl carrier protein have an enzyme
> classification # or is it considered to be a passive acceptor only?

Acyl Carrier Protein, from both eukaryotes and prokaryotes, does not have an
Enzyme Commission number because it has no reported enzyme activity.  It is,
in fact, regarded as a substrate, and as such, appears in the names of enzymes
with which it interacts.  The eukaryotic forms are tightly bound in the fatty
acid synthetase complex, but the prokaryotic forms can be solubilized.  (The
PIR accession numbers for E. coli ACP's are A03398 and A26935.)
                                 Dr. John S. Garavelli
                                 Database Coordinator
                                 Protein Identification Resource
                                 National Biomedical Research Foundation
                                 Washington, DC  20007
                                 GARAVELLI at GUNBRF.BITNET

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