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[Plant-biology] Postdoctoral position at the Carlsberg Laboratory

Anette Henriksen anette at crc.dk
Thu Aug 17 02:21:00 EST 2006

*Postdoctoral position available at the Carlsberg Laboratory**

Protein-protein interactions and regulation of enzymes in the 
peroxisomal **b**eta-oxidation cycle.
*The Biostructure Group at Carlsberg Laboratory studies plant lipid 
metabolism from a structural-biological perspective. The Laboratory was 
set up in Copenhagen 1875 by the founder of Carlsberg to develop a 
scientific basis for malting, brewing, and fermenting operations and it 
has a long record in yeast biology and plant physiology.
The majority of plant fatty acids are decomposed via the peroxisomal 
beta-oxidation cycle. The pathway is a key component in the oxidative 
parts of the biosynthetic pathways leading to the plant hormones 
jasmonic acid and indole-3-acetic acid. The present project aims at 
identifying protein-protein interactions in this pathway and to 
investigate the mechanisms behind substrate channeling. It involves 
X-ray crystallographic structure determination, pull-down assays of 
protein-protein complexes from plant peroxisomes and characterization of 
protein-protein interactions in the peroxisomal b-oxidation cycle by 
small angle scattering, dynamic light scattering and surface plasmon 
resonance. Our laboratory is fully equipped for all aspects of molecular 
biology, protein chemistry, protein crystallography and biophysical 
characterization of proteins.
Applicants must have experience in production and purification of 
recombinant proteins. Experience with molecular biology, macromolecular 
crystallography and/or biophysical characterization of proteins will be 
considered an advantage.
The position is a three-year position with one-year contract 
re-negotiation. Inquiries should be directed to: Anette Henriksen, 
E-mail: anette at crc.dk. To apply, please send a cv including a brief 
description of research interests and accomplishments, and the names and 
addresses of two referees to: Anette Henriksen, Biostructure Group, 
Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Copenhagen, 
Denmark E-mail: anette at crc.dk

Anette Henriksen, Prof., Ph.D.
Carlsberg Laboratory, Biostructure Group,
Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark.
Phone: +45 33275222. Fax: +45 33274765

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