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position open

Thu Jun 5 15:19:00 EST 1997

Plant Molecular Biology/Biotechnology (PMBB) Group/ 
Horticulture and Crop Science
The Ohio State University
Columbus, Ohio USA

A postdoctoral position is available to investigate the sugar 
sensing and signal transduction pathway in higher plants. 
Using a combination of biochemical, genetic and molecular 
approaches, we have identified the first plant sugar sensor, 
hexokinase (Plant Cell 6, 1665-1679; Plant Cell 9, 5-19; 
Trends in Plant Science 2, 208-214). Future projects include: 
the characterization of transgenic Arabidopsis with aberrant 
levels of hexokinase, the identification of other components 
that are involved in the sugar signal transduction pathway 
and the investigation of interactions between sugar and other 
signaling pathways.

A second project to study plant steroid hormones is also 
available. We have identified several classes of Arabidopsis 
mutants that are involved in steroid hormone 
biosynthesis/signaling pathway. A T-DNA tagged brassinolide 
insensitive mutant with extra long life (ell) and 
uncontrolled meristematic activity has been analyzed. ell 
appears to have a lesion in a sterol reductase gene. Future 
work include: the characterization of the ell  mutant, the 
investigation of the function of ELL, and the analysis of 
other mutants.

The position will be in the Plant Molecular 
Biology/Biotechnology (PMBB) Group/ Horticulture and Crop 
Science Department, The Ohio State University, Columbus, Ohio 
USA. Candidates should have demonstrated experience and 
publications in molecular biology, genetics or cell biology. 

Applicants should send a curriculum vitae, a brief statement 
of research interest and names and phone numbers and e-mail 
address of 3 references (PREFERRED BY E-MAIL) to:

Jyan-Chyun Jang
JANG at frodo.mgh.harvard.edu

Department of Molecular Biology
Wellman 1117
Massachusetts General Hospital
Boston, MA 02114
Phone 617-726-5916
Fax	 617-726-6893

PS:	I would be very happy to meet with interested 
individuals at the Madison Arabidopsis Meeting (June 25-29, 

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