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DNA sequencing/info-theory paper in PNAS

S. A. Modena samodena at csemail.cropsci.ncsu.edu
Wed Mar 24 01:49:15 EST 1993

In article <1993Mar23.220831.23581 at ncsu.edu> samodena at csemail.cropsci.ncsu.edu (S. A. Modena) writes:
 As Steven Brenner remarks elsewhere, I *meant* to say SEMI-conservative....

>I might add a side comment or two about one of the "critical readers"
>acknowledged: Myron Brakke.  Brakke (if it's the same one  :^) ) is a plant
>pathologist who years ago simplified the preparative isolation/purification
>of plant virus particles from homogenized leaf material by *inventing*
>sucrose density gradient centrifugation.......and I recall from a
>conversation with Mathew Messelson how critical the timing of that
>invention was to him and Stahl (wasn't it) performing the "famous"
>experiment that UNequivically proved the conservative model of replication
                                         /            \
       should read:                    SEMI-conservative
>for ds-DNA...which if you recall, hinges on exactly the *same* decoding
>scheme for interpreting the results as I mentioned above for working
>through the two-lane sequencing example.  
>|     In person:  Steve Modena     AB4EL                           |
>|     At e-mail:  nmodena at unity.ncsu.edu                           | 
>|                 samodena at csemail.cropsci.ncsu.edu                |

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