I am working on an obligate-intracellular microorganism and would like
to examine population structure among strains. I have tried using an
outer membrane protein, and it does evolve at a pretty fast rate, but
not fast enough. Can anyone suggest another possibility? RAPDs are out
of the question because of host-cell contamination. (I have thought of
the 16S-23S intergenic spacer region, but I'm not sure if it would be
more helpful or not.) Please reply directly to me.