Re: What is the most commom genetic abnormally?
In some cases, such as sickle anemia, the heterozygote (single
gene) may have a selective advantage in a certain population
(i.e. greater resistance to malaria) and is therefore selected
for. Whereas the homozygote (double gene) is likely to die
Does anybody know of a selective advantage of being heterozygous
for hemochromatosis or cystic fibrosis?
If you do not know what hemochromatosis (iron overload) is,
please visit http://www.emi.net/~iron_iod/ and spread the word.
E. Williams, HH Awareness, http://www.geocities.com/HotSprings/5686
Steven B. Harris wrote:
>> In <33A367BC.4B7E at sprynet.com.ns> Elliot Williams
> <kakapo at sprynet.com.ns> writes:
> >What is the most common genetic abnormally?
> >Is hemochromatosis (iron overload) the most common genetic
> >Heterozygous (single gene) 1 in 8
> >Homozygous (double gene) 1 in 200
> >(source: http://www.emi.net/~iron_iod/io42000.html).
> >What are the other common genetic abnormalities?
> >E. Williams
> >kakapo at sprynet.com> >
>> About 1 in 20 carries the gene for cystic fibrosis, with the
> homozygous frequency being about 1 in 4*(20)^2 = 1600. Of course, the
> frequency of these things varies with the population.
>> Steve Harris, M.D.