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What is the SMALLEST DNA BINDING DOMAIN?

Tom Schneider toms at ncifcrf.gov
Sat Jan 11 19:25:49 EST 1997


jstrassw at OPAL.TUFTS.EDU wrote:

: Well, the Bovine Papillomavirus DNA binding domain (minimal) iosonlt 85 AA
: although tit forms a dimer.  It has the aadvantage of many characterized
: mutations, and an excellent crystal structure (1.2A) and  binds
: sequence-specific to a palindropme at 10 -12 M.
: 
: I also study it!

Cool!  What's the sequence logo look like?

  Tom Schneider
  National Cancer Institute
  Laboratory of Mathematical Biology
  Frederick, Maryland  21702-1201
  toms at ncifcrf.gov
  http://www-lmmb.ncifcrf.gov/~toms/



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