I have a set of aligned protein sequences. I can calculate the phylogeny
using neighbour-joining method (PHYLIP).
I would like to be able to:
a. predict a common ancestral sequence
b. compute the divergence in years
How do I go about this?
Also, would it be better to use the DNA sequences?
Please let me have your views and point me in the right direction.
Dr. Shoba RANGANATHAN
Computational Mol Biology & Drug Design Group
Div. of Biochemistry & Mol. Biology
John Curtin School of Medical Research
Australian National University Tel: +616-279-8301
Canberra ACT 0200 Fax: +616-249-0415
Australia. email:Shoba.Ranganathan at anu.edu.au