IUBio

TDT programs

David Duffy davidD at orpheus.qimr.edu.au
Wed Jun 6 22:38:12 EST 2001


Antti-Pekka Laine <aplaine at utu.fi> wrote:

> Does anybody know of any TDT analysis programs that allow changing 
> the expected transmission ratio from 0.5? I've tried several programs but
> haven't seen such feature.

All programs will display the observed transmission ratio, so you can 
simply test this against your own specified null by hand eg

          Child received    
Parent      1       2      Total
------    --------------   -----
1/2         12      6        18

This is a transmission ratio of 66.7% (12/18), which has a 95%
confidence interval of 41.9% to 86.6% (obtainable from standard tables,
or from a stats package).  This is the range of specified null values it
is consistent with at the 5% level.






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