On 27 May 1995, Graham Dellaire wrote:
> Other complex diseases mapped by linkage
> Cystic fibrosis (physical cloning)
> XLA
>> Amyotrophic lateral Sclerosis (ALS) (functional and position cloning)
> Waardenburg syndrome
I wonder what is meant by "complex" here. I thought that cystic fibrosis
and Waardenburg syndrome were "simple" (recessive and dominant,
respectively) Mendelian disorders. What makes them complex? Is there
heterogeneity or what?
Thanks,
Mike
Michael B. Miller, M.S., Ph.D.
Department of Psychiatry (Box 8134)
Washington University School of Medicine
4940 Children's Place, St. Louis, MO 63110
office phone: (314) 362-9428 FAX: (314) 362-9420
WWW Homepage: ftp://sirronald.wustl.edu/pub/mbmiller/mike.htm