Looking for good examples of complex diseases where the pathogenic
mutation has actually been identified and the initial localisation was (at
least partly) through the use of a linkage strategy. Breast cancer is a good
example, senile onset Alzheimer's disease is probably pushing it a bit.
Other suggestions?
Thanks
Dave Curtis (dcurtis at hgmp.mrc.ac.uk)
http://www.iop.bpmf.ac.uk/home/depts/psychmed/general/dcurtis/dcurtis.htm
