Dear Lucien,
Thank you for making your raw data available. If I run your data through a
genotype elimination program I have, we get the output:
1: Pedigree 1 has 172 people.
Genotype List Contains only Incompatible Pairs:
Father 38: Locus 3
The genotype list is: 8/4 4/8 2,
The spouse is person: 10
The spouse's genotype list is: 3/2 1,
So here are the people involved:
1 10 5 1 37 11 11 2 0 2 2 2 4 2 3 1 3 2 4 Ped: 1 Per: 104
1 38 0 0 37 0 0 1 0 1 2 3 8 4 8 0 0 0 0 Ped: 1 Per: 132
1 37 38 10 0 39 39 2 0 2 2 2 8 2 6 1 7 1 2 Ped: 1 Per: 107
1 39 38 10 0 0 40 1 0 2 2 3 4 3 6 3 7 1 4 Ped: 1 Per: 105
1 40 41 10 0 0 0 1 0 1 1 2 7 2 6 1 3 2 8 Ped: 1 Per: 106
^ ^
As you can see, we have:
4/8 x 2/3
|
-----------
| |
2/6 3/6
This is a clear inconsistency. I do not know why UNKNOWN does not catch
this - perhaps it has to do with the fact that person 10 has married
twice?
Best wishes,
-- Dan Weeks --
