IUBio

Linkage proble

Lucien Bachner bachner at Cassini.genethon.fr
Tue Dec 20 05:22:08 EST 1994


Hello everybody

I have a strange mlink problem.
The analysis is a dominant disease in a 7 seven generations pedigree 
with 171 individuals and one loop. 
All files have been checked and look correct.
The results are always -infinity for all thetas,
for any pair of loci (marker-marker or disease-marker).
I have tried classical mlink, and fast and slow versions of
Fastlink/mlink, all on a Sun ipx, and always the same results.
I have also changed "scale" from 2 to 10 in mldefs.h in Fastlink,no differences.
I have tried two versions of unknown, no differences.
I have no error messages or warnings from any program.
I have no more ideas so if you can help me please do it.
Thank you in advance

=====================================================
|            Lucien Bachner                         |
| Laboratoire de Biochimie Genetique,Hopital Cochin.| 
|   123 Bd. Port Royal, 75014 Paris, France.        |
|     Tel: (33 1) 42-34-12-12 ext 3039              |
|     FAX: (33 1) 44-41-15-22                       |
| e-mail : bachner at Cassini.genethon.fr              | 
|          bachner at citi2.fr                         |
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