I am immunologist and have performed some breeding studies in
an attempt to localise a gene which causes autoimmunity. I am
using exclusion mapping to achieve this. Can someone advise
me on what statistical proceedure I should use? The sort of
data I get is:
Only BC1 mice with + phenotype are examined at multiple loci on
a chromosome -
locus 1 4/8 hetrozygotes
locus 2 2/8 hetrozygotes
locus 3 5/8 hetrozygotes
locus 4 0/8 hetrozygotes
locus 5 0/8 hetrozygotes
locus 6 2/8 hetrozygotes
(There is quite a lot more to it than this, and I would be happy to
provide more detail if needed)
Please email, and thanks for any help!
Regards Alan
